Pulling the genome apart: Chromosome segregation during mitosis explained

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Researchers shed light on the protein complexes and processes that enable microtubules to bind to the centromeres of chromosomes and redistribute them to the daughter cells during mitosis. Via experiments including partial protein deletion, chimeric protein production, and measurement of microtubule pulling force, the team showed that interaction of the Ndc80 complex with the CENP-T pathway of kinetochores, not the CENP-C one, is essential for successful cell division.

from Latest Science News -- ScienceDaily https://ift.tt/2DdL9NP

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