★★★★★ (ცɮ ცαηℊℊą) ★★★★★

More than 370,000 people have been ordered to evacuate as Hurricane Michael heads towards Florida. from BBC News - US & Canada https://ift.tt/2PpucDb

A new method will enable researchers to directly observe and capture atomic motions at surfaces and interfaces in real time. from Latest Science News -- ScienceDaily https://ift.tt/2A1EILw

Antibiotic resistance in bacteria is a growing global health crisis. Now, new research provides crucial details on bacterial defenses and how we could undermine them. from Latest Science News -- ScienceDaily https://ift.tt/2QCWDO8

Enhancing the speed and reducing the size of data storage devices requires gaining control over the force making electrons spins. In a recent study scientists have developed a new theory to predict the complex dynamics of spin procession in materials subjected to ultra-short laser pulses. The advantage of this approach is that it is predictive. from Latest Science News -- ScienceDaily https://ift.tt/2Nzm4y6

High levels of air pollutants, especially fine particulate matter (PM2.5) and to a lesser extent, ozone, may be linked to a heightened risk of developing mouth cancer, suggests the first study of its kind. from Latest Science News -- ScienceDaily https://ift.tt/2RK0UAW

Researchers used eBird data to convince California to list the Tricolored Blackbird as endangered. from Latest Science News -- ScienceDaily https://ift.tt/2Ejlfdo

A new study found that while dead whales are valuable sources of fat and protein for some polar bears, this resource will likely not be enough to sustain most bear populations in the future when the Arctic becomes ice-free in summers. from Latest Science News -- ScienceDaily https://ift.tt/2pLvv4n

New research in a mouse model suggests that the drug rapamycin can reverse autism-like social deficits -- but only if given early. The study is the first to shed light on the crucial timing of therapy to improve social impairments in a condition associated with autism spectrum disorder. Its findings could help inform future clinical trials in children with tuberous sclerosis complex. from Latest Science News -- ScienceDaily https://ift.tt/2EcqtI2

A root extract of the Fallopia multiflora, or Chinese knotweed, has special properties: it enables the nematode C. elegans to live longer and protects it from oxidative stress, according to a new study. from Latest Science News -- ScienceDaily https://ift.tt/2Od3Mbn

Medicines commonly prescribed to reduce people's risk of heart attack may have limited use for treating other diseases, research suggests. from Latest Science News -- ScienceDaily https://ift.tt/2ORfiZm

Even long before medieval inhabitants reclaimed land and raised dykes at a large scale, humans have had a strong impact on river behavior in the Dutch delta plain. Physical geographers have demonstrated that two present Rhine branches developed stepwise in the first centuries CE, because of two combined man-induced effects. from Latest Science News -- ScienceDaily https://ift.tt/2PtyLg1

Scientists have discovered a gene that appears to play a vital role in pheromone sensing. The gene is conserved across fish and mammals and over 400 million years of vertebrate evolution, indicating that the pheromone sensing system is much more ancient than previously believed. from Latest Science News -- ScienceDaily https://ift.tt/2yf3ir7

Consuming too much vitamin A may decrease bone thickness, leading to weak and fracture prone bones, according to a new study in mice. from Latest Science News -- ScienceDaily https://ift.tt/2Pq4y1g

New research suggests that a type of 'supercharged' immune cell could be mass-produced to help fight cancer. from Latest Science News -- ScienceDaily https://ift.tt/2yf3ExX

Planned intermittent fasting may help to reverse type 2 diabetes, suggest doctors after three patients in their care, who did this, were able to cut out the need for insulin treatment altogether. from Latest Science News -- ScienceDaily https://ift.tt/2ILE1ZM

Young people in England aren't just drinking less alcohol -- a new study shows that more of them are never taking up alcohol at all, and that the increase is widespread among young people. from Latest Science News -- ScienceDaily https://ift.tt/2Nypa5A

Researchers are using metallic alloys to lighten the load and enhance the power of Soldier devices used on the battlefield. from Latest Science News -- ScienceDaily https://ift.tt/2OLUd2G

New research could help bring about the kind of far-reaching changes deemed necessary in the UN's dire new climate change report. Scientists found that when westerly winds in the Antarctic Ocean strengthen during the austral summer (Oct.-Feb.), surface waters in the region acidify faster than can be accounted for by increases in carbon dioxide from the atmosphere alone. from Latest Science News -- ScienceDaily https://ift.tt/2Nv93G0

In an era of fact-checking and 'alternative facts,' many people simply choose not to believe research findings and other established facts, according to a new article. from Latest Science News -- ScienceDaily https://ift.tt/2OT70jC

DNA from people who suffer from major depression is biologically older than that of healthy people by on average 8 months, suggesting that they are biologically older than their corresponding calendar age. This effect was greater in people who have had childhood trauma, such as violence, neglect or sexual abuse, who show a biological age around a year older than their actual age. from Latest Science News -- ScienceDaily https://ift.tt/2Ny2X7z

Females of a socially monogamous passerine, the Japanese great tit (Parus minor), become more promiscuous after hatchings fail in the first breeding attempt -- apparently attempting to ensure successful reproduction. from Latest Science News -- ScienceDaily https://ift.tt/2OR4CK8

You turn on a switch and the light switches on because electricity 'flows'. The usual perception is that this is like opening a faucet and the water starts to flow. But this analogy is misleading. The flow of water is determined by the theory of hydrodynamics, where the behavior of the fluid requires no knowledge of the movements of individual molecules. from Latest Science News -- ScienceDaily https://ift.tt/2C3o53L

After feuding on-off for almost a decade, the pair now back opposite sides in the US mid-terms. from BBC News - US & Canada https://ift.tt/2NyhHU4

Researchers have discovered a micropeptide molecule that can restore normal heart function in mice, according to a new study. from Latest Science News -- ScienceDaily https://ift.tt/2RCOOt6

Scientists have modeled the first step in human development in a laboratory with the goal of better understanding how organs form. In the new study, the researchers edited groups of human pluripotent stem cells to silence genes important for cellular mechanics. The alterations prompted the cells to move around and self-organize until they were divided into two groups: Those that had been manipulated and those that had not. from Latest Science News -- ScienceDaily https://ift.tt/2Ea1xkw

Antarctica's sandy polar desert, the McMurdo Dry Valleys, has undergone changes over the past decade and the recent discovery of thawing permafrost, thinning glaciers and melting ground ice by a research team are signs that rapid and widespread change could be on the horizon. from Latest Science News -- ScienceDaily https://ift.tt/2IKG2Fl

The founder of the Toronto-based beauty brand said its stores would close because of "criminal activity". from BBC News - US & Canada https://ift.tt/2C5Lhye

As the US ambassador to the UN resigns, she leaves her position singing the praises of the president's son-in-law. from BBC News - US & Canada https://ift.tt/2INrftR

Google announced that its social network, Google+, will shut down, after reports of a data breach that affected millions of users. The announcement left many surprised that Google+ still existed. from Technology : NPR https://ift.tt/2IPutgs

But President Trump says he can't give his daughter the UN ambassadorship because he would be accused of nepotism. from BBC News - US & Canada https://ift.tt/2RCBXar

"One test report indicated that the test team was able to guess an administrator password in nine seconds," the Government Accountability Office says. (Image credit: Yuri Gripas/Reuters) from Technology : NPR https://ift.tt/2PqxkyC

Once a familiar sight by the side of the road, neon motel and drive-in signs are becoming a thing of the past. from BBC News - US & Canada https://ift.tt/2IPt89q

New data shows that the divorce rate in the US has fallen and 'millennial marriage' may be a factor. from BBC News - US & Canada https://ift.tt/2QCRgyw

The McIntosh apple was once the most popular apple in North America, but its time in the sun is over. from BBC News - US & Canada https://ift.tt/2yb93WW

A new species of owlet moth recently discovered to inhabit high-elevation mountains in western North America has been named after the Greek mythological character Icarus. from Latest Science News -- ScienceDaily https://ift.tt/2QJzZ75

A location often earmarked as a potential habitat for extra-terrestrial life could prove to be a tricky place for spacecraft to land, new research has revealed. from Latest Science News -- ScienceDaily https://ift.tt/2A2WPkx

Researchers have developed two new illusions that reveal how the senses can influence each other -- in particular, how sound can give rise to visual illusions. These illusions occur so quickly that they illustrate a phenomenon called postdiction (as opposed to prediction) in which a stimulus that occurs later can retroactively affect our perceptions of an earlier event. from Latest Science News -- ScienceDaily https://ift.tt/2OjcPYb

Some molecules change their spatial structure when exposed to light -- in other words, they look different in light and darkness. What exactly happens during the conversion has not yet been researched in detail. from Latest Science News -- ScienceDaily https://ift.tt/2QEOUzc

Scientists have created fruit flies carrying reconstructed ancient genes to reveal how ancient mutations drove major evolutionary changes in embryonic development--the impact of which we see today. from Latest Science News -- ScienceDaily https://ift.tt/2INdQ4S

The oldest flying squirrel fossil ever found has unearthed new insight on the origin and evolution of these airborne animals. from Latest Science News -- ScienceDaily https://ift.tt/2QEWVEl

Climate change's effect on coastal ecosystems is very likely to increase mortality risks of adult oyster populations in the next 20 years. from Latest Science News -- ScienceDaily https://ift.tt/2yaRCWh

Most of the fauna in the Arctic region take part in pollinating, yet during the busiest flowering weeks, there's a shortage of such services. A recent study indicates that the pollination services provided to plants and, thus, the plants' ability to produce seeds are dependent on the timing of the blooming season, and on how many other species are in bloom simultaneously. from Latest Science News -- ScienceDaily https://ift.tt/2C4KzkJ

Researchers have analyzed the composition and structure of faraway exoplanets using statistical tools. Their analysis indicates whether a planet is earth-like, made up of pure rock or a water-world. The larger the planet, the more hydrogen and helium surround it. from Latest Science News -- ScienceDaily https://ift.tt/2CxwWeV

Scientists have placed light-absorbing gold nanoclusters inside a bacterium, creating a biohybrid system that produces a higher yield of chemical products, such as biofuels, than previously demonstrated. The biohybrid captures sunlight and carbon dioxide to make chemicals useful not only on Earth but also in the exotic environment of space. from Latest Science News -- ScienceDaily https://ift.tt/2RBzQ6C

ফের উদ্বেগ, আশঙ্কার কারণ হয়ে উঠল জিকা ভাইরাস। ওই ভাইরাসে আক্রান্ত হওয়ার একের পর এক ঘটনার খবর আসছে রাজস্থানের জয়পুর থেকে। মঙ্গলবার আক্রান্ত হয়েছেন আরও সাত জন। রাজস্থানের অতিরিক্ত মুখ্য সচিব (স্বাস্থ্য) বীনু গুপ্তা এ দিন টুইট করে জানিয়েছেন, এখনও পর্যন্ত শুধু জয়পুরেই আক্রান্তের সংখ্যা ২৯। ঘটনায় উদ্বিগ্ন প্রধানমন্ত্রীর কার্যালয়ের পক্ষ থেকে বিস্তারিত রিপোর্ট চাওয়া হয়েছে কেন্দ্রীয় স্বাস্থ্য মন্ত্রকের থেকে। রাজস্থানের স্বাস্থ্য দফতর সূত্রের খবর, জয়পুরের এসএমএস হাসপাতালে আক্রান্তদের আলাদা ভাবে রেখে চিকিৎসা চলছে। পরিস্থিতির ওপর নজর রাখতে ন্যাশনাল সেন্টার ফর ডিজিজ কন্ট্রোলে খোলা হয়েছে একটি বিশেষ কন্ট্রোল রুম। from Zee24Ghanta: Health News https://ift.tt/2yqOcOC

The company says it discovered and patched the issue in March, but did not immediately disclose it. There is no evidence, it said, that a third party was aware of the bug or misused profile data. (Image credit: Paul Sakuma/AP) from Technology : NPR https://ift.tt/2CycyKz

P.W. Singer and Emerson Brooking say social media has been manipulated to fuel popular uprisings and affect the course of military and political campaigns. Their new book is LikeWar. from Technology : NPR https://ift.tt/2Pp6bME

An antipsychotic drug that is used to treat Tourette's syndrome shows promising results against triple-negative breast cancer in a study of cells and mice. from Breast Cancer News From Medical News Today https://ift.tt/2ybrxXn

Saint John's University senior defensive end Nathan Brinker (Avon, Minn./Holdingford) has a special relationship with a young cancer survivor from his hometown. - Randy Shaver Cancer Research & Community Fund from Saint John's University https://ift.tt/2ynNQZ2

The 1972 Clean Water Act has driven significant improvements in US water quality, according to the first comprehensive study of water pollution over the past several decades. The team analyzed data from 50 million water quality measurements collected at 240,000 monitoring sites throughout the US between 1962 and 2001. Most of 25 water pollution measures showed improvement. from Latest Science News -- ScienceDaily https://ift.tt/2C69GDV

Ants are neat: when they move into a new nest box, they spend the first days cleaning it thoroughly. Despite keeping the nest clean, using poison within the nest is dangerous and can kill unprotected brood. However, the silk cocoon that surrounds the ant's sensitive pupae protects them from any harmful effects. from Latest Science News -- ScienceDaily https://ift.tt/2E9chzn

The amount of plastic washing up onto the shores of remote South Atlantic islands is 10 times greater than it was a decade ago, according to new research. Scientists investigating plastics in seas surrounding the remote British Overseas Territories discovered they are invading these unique biologically-rich regions. This includes areas that are established or proposed Marine Protected Areas (MPAs). from Latest Science News -- ScienceDaily https://ift.tt/2CzoRq7

In string theory, a paradigm shift could be imminent. In June, a team of string theorists published a conjecture which sounded revolutionary: String theory is said to be fundamentally incompatible with our current understanding of 'dark energy'. A new study has now found out that this conjecture seems to be incompatible with the existence of the Higgs particle. from Latest Science News -- ScienceDaily https://ift.tt/2RDh9Qa

Next time you're stung by a wasp or a honeybee, consider the elegantly designed stinger that caused you so much pain. Researchers found that the stingers of the two species are about five times softer at the tip than at the base to make it easier to pierce skin. The stingers are harder closer to the insect's body so they don't bend too much, or break, as you yelp in agony. from Latest Science News -- ScienceDaily https://ift.tt/2E9nW1m

Do you marvel at your friend's ability to assemble complex furniture and navigate a new city, or do you all-around groan at your own lack of spatial skills? Don't fret! A new study found that you, too, can improve your spatial reasoning with practice. from Latest Science News -- ScienceDaily https://ift.tt/2IK7QJZ

JPL's paint shop does 1,000 jobs a year. While every piece of spacecraft that comes through the shop is important, one headed for the Red Planet provides a little extra oomph. from News and Features - NASA's Jet Propulsion Laboratory https://ift.tt/2Cxg1cn

There's new evidence that a short section of fault in the California desert connects known faults in California and Mexico into one long, continuous system. from News and Features - NASA's Jet Propulsion Laboratory https://ift.tt/2C5BMir

প্রথম পর্যায়ে ক্যানসার ধরা পড়লে, চিকিত্সা তাড়াতাড়ি শুরু হলে সেরে ওঠার সম্ভাবনাও থাকে। এর জন্য গলার ক্যানসারের প্রাথমিক লক্ষণগুলির সম্পর্কে জানা দরকার। from Zee24Ghanta: Health News https://ift.tt/2CyfRBD

COLLEGEVILLE, Minn. – The Bear WBHR-660 AM will broadcast a special Football Weekly radio show this Thursday, Oct. 11, from 6-8 p.m. at the Blue Line Sports Bar & Grill in Sartell. - Listen from Saint John's University https://ift.tt/2yoLyZN

Invasive lobular breast cancer affects the lobules, which contain glands that produce breast milk. This type of cancer can spread to other parts of the breast and may affect other areas of the body. In this article, learn more about treatments, remission, and outlook. from Breast Cancer News From Medical News Today https://ift.tt/2pJ9Uth

Scientists have discovered that regular use of the party drug GHB, and especially unconsciousness following GHB use, is associated with brain changes including negative effects on long-term memory, working memory, IQ, and higher levels of stress and anxiety. from Latest Science News -- ScienceDaily https://ift.tt/2CBf6rm

Results from the largest study (nearly a million cycles) to investigate the prevalence and causes of multiple pregnancies after single embryo transfer (SET) finds that using frozen thawed embryos for SET, maturing the fertilized egg (blastocyst) in the laboratory for five or six days before SET, and assisted hatching could increase the risk. from Latest Science News -- ScienceDaily https://ift.tt/2OgJQnK

জেনে নেওয়া যাক তেমনই কিছু কারণ ধূমপান ছাড়াও যেগুলি ফুসফুসে ক্যান্সারের ঝুঁকি বাড়িয়ে দিচ্ছে দিনের পর দিন। from Zee24Ghanta: Health News https://ift.tt/2OblonQ

America's ambassador to the UN Nikki Haley, senior Trump cabinet member, has resigned unexpectedly, US media report. from BBC News - US & Canada https://ift.tt/2OffCld

Some long-held teaching practices have not been effective, such as customizing instruction to learner styles, according to a  - More -  from ASCD SmartBrief https://ift.tt/2NzTpJk

The number of high-school general equivalency diplomas issued in the US fell by more than 45% between 2012 and 2016, accordin - More -  from ASCD SmartBrief https://ift.tt/2ONfkl7

Some educators in the US are using Columbus Day, celebrated Monday, to teach students about the Native American population.  - More -  from ASCD SmartBrief https://ift.tt/2NxDH1w

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Students at a school in Missouri are building robots that have a practical purpose in their lives as part of a science, techn - More -  from ASCD SmartBrief https://ift.tt/2Oc33XX

A network of students in Kentucky has launched an organization aimed at raising students' voices in conversations about menta - More -  from ASCD SmartBrief https://ift.tt/2yzyUHx

Eighteen recipients will share about $50 million from this round of federal Education Innovation and Research grants.  - More -  from ASCD SmartBrief https://ift.tt/2OftFr6

About 4,200 sophomores and juniors are expected to take the PSAT exam for free this week in a Texas school district.  - More -  from ASCD SmartBrief https://ift.tt/2yus1H8

Sexual minority adolescents had a 3.5 times increased likelihood of attempting suicide, compared with heterosexual peers, res - More -  from ASCD SmartBrief https://ift.tt/2Oio3MR

Join Brad Gosche, vice president and lead certified trainer at the Global Fluency Institute, for a two-part ASCD webinar seri - More -  from ASCD SmartBrief https://ift.tt/2yurN2K

The arts hold tremendous potential to foster students' creativity, improve academic performance, and boost social-emotional d - More -  from ASCD SmartBrief https://ift.tt/2OftFaA

Benjamin Rush, physician and Founding Father from ASCD SmartBrief https://ift.tt/2yrrdmA

Evidence of a variable but progressively drying climate coincides with a major shift in stone-tool-making abilities and the appearance of modern Homo sapiens. Sediment cores obtained by the Hominin Sites and Paleolakes Drilling Project provide the first continuous environmental context for the diverse archeological evidence recovered from nearby localities in the East African rift valley. from Latest Science News -- ScienceDaily https://ift.tt/2QCBhQW

Salt is essential for life. As ancient civilizations evolved from hunters and gatherers to agrarian societies, it has not been clear how people acquired this mineral that is a biological necessity. However, an anthropologist has discovered remnants of an ancient salt works in Belize that provide clues on how the ancient Maya at the peak of their civilization more than 1,000 years ago produced, stored and traded this valuable mineral. from Latest Science News -- ScienceDaily https://ift.tt/2NxtCS9

The pair will discuss prison reform, gang violence and manufacturing resurgence in the US. from BBC News - US & Canada https://ift.tt/2Pl2h7r

The tech giant, under scrutiny over a data lapse, has scrapped plans to bid for a high-profile contract. from BBC News - US & Canada https://ift.tt/2zZUhDI

A new analysis that uses high-resolution data for 24 ocean regions in Africa, Europe, North and South America and Australasia shows that 14 percent of the overall seafloor shallower than 1,000 meters (3,280 feet) is trawled. The analysis shows that the footprint of bottom-trawl fishing on continental shelves and slopes across the world's oceans often has been substantially overestimated. from Latest Science News -- ScienceDaily https://ift.tt/2C2ygWd

A study has uncovered a brain-signaling pathway that can be pharmacologically manipulated in mice to reverse an autism-related pathway. Using an experimental drug targeting this pathway, researchers normalized the disrupted physiology and behavior of these mice. Moreover, effects were seen in adult mice, suggesting a possible route to developing medications for adults with autism spectrum disorder. Remarkably, the study also showed physiological changes linked to gut function in the mice, a medical comorbidity of ASD. from Latest Science News -- ScienceDaily https://ift.tt/2PoEGTt

For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth. Researchers offer proof-of-concept for prenatal use of a sophisticated, low-toxicity tool that efficiently edits DNA building blocks in disease-causing genes. from Latest Science News -- ScienceDaily https://ift.tt/2yaHcG5

For the first time, a team of researchers has found a specific place in the human genome that raises a person's risk of erectile dysfunction. The discovery is a significant advancement in the understanding of the genetics underlying erectile dysfunction. from Latest Science News -- ScienceDaily https://ift.tt/2pLrnRO

Snapdragons are tall plants, and flower in a range of colors. In Spain, where snapdragons grow wild, these flower colors show a remarkable pattern: areas of magenta and yellow blooming flowers are separated by just a two kilometer long stretch in which flower colors mix. Scientists have investigated the causes of this pattern and identified the genes responsible for flower color difference from DNA sequence data. from Latest Science News -- ScienceDaily https://ift.tt/2Nx6ljc

A new study shows that Atlantic salmon use the Earth's magnetic field as a navigational tool -- much like their cousins, Pacific salmon -- and don't lose that ability through several generations of fish even after they have been transplanted into a land-locked lake. from Latest Science News -- ScienceDaily https://ift.tt/2ILl7Sx

Scientists have now completed an exceptionally detailed map of the brain's memory bank, the hippocampus. Intricate insight into hippocampus' structure and function opens new opportunities to treat diseases such as Alzheimer's. from Latest Science News -- ScienceDaily https://ift.tt/2OP7DuK

A team of researchers applied a newly developed editing tool to target and correct genetic mutations. By doing so, the researchers healed mice suffering from a genetic metabolic disorder that also affects humans. from Latest Science News -- ScienceDaily https://ift.tt/2PnD7VP

Researchers have developed the first example of a bioelectronic medicine: an implantable, biodegradable wireless device that speeds nerve regeneration and improves healing of a damaged nerve. Their device delivered pulses of electricity to damaged nerves in rats after a surgical repair process, accelerating the regrowth of nerves and enhancing the recovery of muscle strength and control. The device is the size of a dime and the thickness of a sheet of paper. from Latest Science News -- ScienceDaily https://ift.tt/2NvjucA

Tens of thousands of people have been told to evacuate before the storm hits Florida on Wednesday. from BBC News - US & Canada https://ift.tt/2OU2AJD

Toddlers with asthma are more likely to become obese children, according to the biggest study on the matter to date. from Latest Science News -- ScienceDaily https://ift.tt/2pKxhlW

Each year 15 million infants are born preterm and face high risks of short- and long-term complications, including sepsis, severe inflammation of the gut, and neurodevelopmental disorders. A new report demonstrates a link between prenatal inflammation and postnatal immune status and organ function in preterm pigs, suggesting that early intervention (eg, antibiotics or anti-inflammatory drugs) may be warranted for infants born preterm with signs of inflammation of fetal membranes. from Latest Science News -- ScienceDaily https://ift.tt/2IJ1rih

An inability to properly use the essential mineral manganese could be to blame for some cases of severe scoliosis, according to a new study. from Latest Science News -- ScienceDaily https://ift.tt/2PpOug2

How one man's mother unwittingly made him an internet celebrity, for all the wrong reasons. from BBC News - US & Canada https://ift.tt/2Czk7AY

Speculation swirled only recently that the man in charge of the Russia probe could be fired. from BBC News - US & Canada https://ift.tt/2pI3pXx

David Greene talks to Douglas MacMillan of The Wall Street Journal about how Google exposed the private data of hundreds of thousands of Google+ users and then opted not to disclose the issue. from Technology : NPR https://ift.tt/2E8eevY

Trump blasts Democrats for trying to destroy Supreme Court Justice Brett Kavanaugh. The Wall Street Journal reports on a software glitch in Google+ that went unreported. Interpol's president resigns. from Technology : NPR https://ift.tt/2RzODil

Researchers have discovered that the drug estradiol may work as a new treatment for a type of triple-negative breast cancer, which is highly aggressive. from Breast Cancer News From Medical News Today https://ift.tt/2zZBkkm

With 28 days to go to the mid-term elections, here's our daily round-up of the main stories. from BBC News - US & Canada https://ift.tt/2pIJQyg