Drugs of abuse: Identifying the addiction circuit

What happens in the brain of a compulsive drug user? Neurobiologists have discovered that the brain circuit connecting the decision-making region to the reward system is stronger in compulsive animals. The researchers also found that by decreasing the activity of this circuit, compulsive mice were able to regain control and that conversely, by stimulating the connection a mouse that initially remained in control became addicted.

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